ARIMIDEX

Arimidex (Anastrozole)

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Arimidex is a drug that consists of Anastrozole compound, and is used for the treatment of breast cancer in women. Arimidex (Anastrozole) is generally used for the treatment of postmenopausal breast cancer; however, Arimidex can be used for treating any kind of breast cancer. Arimidex (Anastrozole) comes under the category of anti-estrogen and is a potent and highly selective non-steroidal aromatase inhibitor. Arimidex (Anastrozole) is manufactured by AstraZeneca.

What should Arimidex (Anastrozole) be used for?
Arimidex (Anastrozole) is used in the treatment of advanced or locally advanced breast cancer, and as additional treatment in early breast cancer.

The breast is a gland designed to make milk. The lobules in the breast make the milk, which then drains through the ducts to the nipple. Similar to other body parts, the cells in the breasts grow and then rest in cycles. Genes in the cell’s nucleus control the periods of growth and rest in each cell, where the nucleus is the control room of the cell. The cells grow properly when genes work in a proper fashion, and on the other hand the growth of the cell gets disturbed if the gene function gets disturbed. So, breast cancer is an uncontrolled growth of breast cells.

Cancer can break through normal breast tissue barriers and spread to other parts of the body. According to the results most cancers are due to some dysfunction of the bodies’ organs or tissues rather than because of inheritance. As far as breast cancer is concerned, the chances of it happening increase with age and doubles every 10 years until the menopause rate decreases. There are some important points to be noted about breast cancer. They are:

  • Breast cancer is generally not painful and women do not feel unwell with it. So, it is important to keep a regular self check on the breasts.
  • Breast cancer is commonly diagnosed by breast screening in women who have no symptoms.
  • A lump in the breast is the sign of breast cancer. In many cases, the woman herself will first suspect the disease because she notices a lump or an area of lumpiness or irregularity in her breast tissue. This may happen when she is examining her breasts or while washing or applying lotion to her breasts, or the lump may be visible.

How does Arimidex (Anastrozole) work?
In post-menopausal women, oestradiol is produced primarily from the conversion of androstenedione to oestrone through the aromatase enzyme complex in peripheral tissues. Oestrone is subsequently converted to oestradiol. Reducing circulating oestradiol levels has been shown to produce a beneficial effect in women with breast cancer.

The female hormone oestrogen stimulates some breast cancers to grow. These are described as hormone sensitive or receptor positive tumors. Postmenopausal women do continue to produce oestrogen. This is mostly produced when other hormones are converted into oestrogen by an enzyme known as aromatase, which is found in the liver and the fatty tissues of the body. Arimidex (Anastrozole) works by stopping this conversion from taking place so that the amount of oestrogen circulating in the body is reduced.

Arimidex (Anastrozole) acts on cancer cells, including those, which have spread. We know that in some women there are small numbers of cancer cells that have spread beyond the breast but cannot be detected by scans. Arimidex (Anastrozole) and other medicines can kill these cells or prevent them from growing for many months and years after surgery with or without radiotherapy. This is called adjuvant treatment.

In some patients with larger but operable breast cancers, the medicines can be used before surgery to shrink the cancer. This allows some women who would initially have required a mastectomy to be treated by less extensive surgery. If the cancer has already spread at the time it is first diagnosed or a patient who is treated for early breast cancer develops a recurrence of the cancer at some other site in the body, then the only practical way of treating these two groups of patients is by medicines.

The medicines for treating breast cancer fall into two groups: hormones and chemotherapy. Whether the patient receives hormone therapy or chemotherapy will depend on the size of the tumor, type of tumor (including the grade) and whether the tumor has spread to involve the lymph glands.

A prescription is required to get Arimidex (Anastrozole)!
Cancer is not something that can be taken lightly. It is a very serious problem and the person suffering from this needs proper care, guidance and attention. Breast cancer is one of the cancers that women face during post menopause age. So, one must consult a specialist of this field before taking Arimidex (Anastrozole) or any other medicine for this purpose.

In what dosage amount should Arimidex (Anastrozole) be taken?
Arimidex (Anastrozole) comes in the form of tablets and should be taken once daily. But, an oncologist must be consulted before taking Arimidex (Anastrozole). Intake should not be stopped without the advice of the doctor. If a dose is missed, there is no need of taking an extra dose the next day, and the treatment should be continued as it is.

For what time duration should Arimidex (Anastrozole) be taken?
Arimidex (Anastrozole) has to be taken for at least 4-5 years, if the cancer is in its primary stage. However, for local recurrence or secondary disease continue taking Arimidex for as long as the breast cancer remains under control.

Precautions to be taken while using Arimidex (Anastrozole)!

  1. Arimidex (Anastrozole) should be taken under doctor’s guidance if a lady suffers from osteoporosis.
  2. Arimidex should not be taken if one is allergic to Arimidex or any other specific drug.
  3. Arimidex (Anastrozole) should not be taken if a lady is breastfeeding or is pregnant.
  4. One must not take drugs containing oestrogen, such as the contraceptive pill or HRT, should not be taken while taking Armidex because they stop the effective working of Arimidex.
  5. Arimidex (Anastrozole) should not be used if there is a problem of the kidney or liver.

What side effects does Arimidex (Anastrozole) have?
As such there are no major side effects seen up until now by the use of Arimidex (Anastrozole), but some of the following may be there, with their intensity varying from person to person. Following are some of the side effects of Arimidex:

  1. Weakness
  2. Vaginal dryness
  3. Nausea
  4. Hair getting thinner
  5. Stiffness
  6. Vomiting
  7. Loss of appetite
  8. Diarrhea
  9. Headache
  10. Joint pain
  11. Skin rash
  12. Sleepiness
  13. Vaginal bleeding

Storage conditions for Arimidex (Anastrozole)!
Arimidex (Anastrozole) should be stored at room temperature and the place where Arimidex is kept should not have excessive moisture and temperature. However, Arimidex (Anastrozole) should be kept in the container it came in, tightly closed, and out of reach of children. Also, as per the general indications for any medicine, Arimidex should also be thrown away if it is outdated.

Where to buy Arimidex (Anastrozole) from?
Buy Arimidex (Anastrozole) from Online Canadian Pharmacy, at discounted rates. For more information about buying of Arimidex log on to Arimidex Prices. Jan Drugs pharmacy provides you with drugs at cheap and affordable prices. One can order the medicine and pay through VISA, MasterCard or international money order.

Why Arimidex (Anastrozole) from Canada?
Online Canadian Pharmacy gives you Arimidex (Anastrozole) at very cheap rates. The reason behind this is the regulation of prices by the Canadian government and also because of the favorable exchange rate. Since, the Canadian dollar is cheaper as compared to the US Dollars, so one can buy more Arimidex from Canada, thereby saving a lot of money.

Major Drug (Arimidex and other cancer drug) Manufacturers

  • Pharmacia
  • AstraZeneca
  • Aventis Pharmaceuticals
  • Berk
  • Novartis
  • Bristol-Myers Squibb
  • Rosemont

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